Feb

12

Childhood Obesity News - Premature death linked to childhood obesity, glucose intolerance, hypertension - Endocrine Today

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Obesity, glucose intolerance and hypertension in children without diabetes appear to be significant predictors of premature death from endogenous causes later in life. Proportional hazard models adjusted for baseline age, sex, birth cohort and tribe (Pima or Tohono O’odham) were used to determine if these risk factors were correlated with death before the age of 55 years. Children in the highest quartile of BMI had significantly higher rates of death from endogenous causes — more than double compared with children in the lowest quartile (IRR=2. Children in the highest quartile of two-hour plasma glucose levels during a 75-g oral glucose tolerance test had a 73% higher risk of death linked to endogenous causes compared with children whose glucose levels were in the lowest quartile (IRR=1. The researchers postulated that the association between premature death from endogenous causes and cholesterol levels may be related to the low proportion of deaths related to cardiovascular disease (13. Further, “cholesterol levels … are lower in American Indians than they are in most other ethnic groups, a finding that may partially explain the absence of association for this trait. Read Childhood Obesity

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